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Symbol Name ID |
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase MGI:87859 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Splenomegaly |
| Disease(s) Associated with ABL1 | |
| chronic myeloid leukemia |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal myocardial fiber morphology |
increased myocardial fiber number |
myocardial fiber disarray |
abnormal trabecula carnea morphology |
abnormal myocardium compact layer morphology |
abnormal heart morphology |
dilated heart atrium |
thick interventricular septum |
increased heart weight |
enlarged heart |
heart hyperplasia |
abnormal heart ventricle morphology |
increased heart ventricle size |
thick ventricular wall |
increased fetal cardiomyocyte proliferation |
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| Availability | Mouse Genotype | ||||||||||||||||
| Abl1tm1Goff/Abl1tm1Goff | |||||||||||||||||
| Abl1tm1Mlg/Abl1tm1Mlg | *! | ! | |||||||||||||||
| Abl1tm1Goff/Abl1tm1Goff Tg(Myh6-cre)2182Mds/0 (conditional) |
* | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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